Treatment of type 2 diabetes: challenges, hopes, and anticipated successes

This review focuses on novel targets and mechanisms and developments (e.g. smart insulin preparation with a glucose-dependent mode of action). Potential clinical use of the salutary adipokine adiponectin, the hepatokine fibroblast growth factor (FGF) 21 and a GLP-1, are discussed

The Lancet Diabetes & Endocrinology