Use of tyrosine kinase inhibitors for paediatric Philadelphia chromosome-positive acute lymphoblastic leukaemia: a systematic review and meta-analysis

Review of 2 RCTs and 4 cohort studies (n=536) found adding tyrosine kinase inhibitors to chemotherapy probably improves overall survival (OS) and event free survival, but the results were not statistically significant. Dasatinib was superior to imatinib

BMJ Open