Vaccine effectiveness of live attenuated and trivalent inactivated influenza vaccination in 2010/11 to 2015/16: the SIVE II record linkage study

Study (n=1.25 million) found the live attenuated vaccine was safe and effective in children. The trivalent vaccine was safe and significantly effective in most seasons for 18-64yr olds, but the effectiveness in people aged ≥65yrs was only statistically significant in 1 season.

National Institute for Health and Care Excellence